Robust treatment planning with conditional value at risk chance constraints in intensity-modulated proton therapy
نویسندگان
چکیده
منابع مشابه
Recent Advances in Intensity Modulated Proton Therapy Treatment Planning Optimization
Radiation therapy is a non-invasive treatment modality for cancer patients. Radiation therapy treatment planning for cancer patients provides many challenging optimization problems. Various variables of a treatment plan need to be optimized so that the resulting plan can kill all cancerous cells while minimizing damage on the patient’s normal tissues. Intensity modulated proton therapy (IMPT) h...
متن کاملIntensity modulated proton therapy.
Intensity modulated proton therapy (IMPT) implies the electromagnetic spatial control of well-circumscribed "pencil beams" of protons of variable energy and intensity. Proton pencil beams take advantage of the charged-particle Bragg peak-the characteristic peak of dose at the end of range-combined with the modulation of pencil beam variables to create target-local modulations in dose that achie...
متن کاملA critical evaluation of worst case optimization methods for robust intensity-modulated proton therapy planning.
PURPOSE To critically evaluate and compare three worst case optimization methods that have been previously employed to generate intensity-modulated proton therapy treatment plans that are robust against systematic errors. The goal of the evaluation is to identify circumstances when the methods behave differently and to describe the mechanism behind the differences when they occur. METHODS The...
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Purpose: Combination of Prostate Seed Implant (PSI) with External Beam Radiation Therapy (EBRT) remains as an attractive option for patients with intermediate or high-risk prostate cancer. One of the most widely used approaches is to use external beam radiation therapy (EBRT) to deliver boost doses after permanent prostate seed implant (PSI). In this study, the feasibility of using Intensity Mo...
متن کاملImproved Beam Angle Arrangement in Intensity Modulated Proton Therapy Treatment Planning for Localized Prostate Cancer
PURPOSE This study investigates potential gains of an improved beam angle arrangement compared to a conventional fixed gantry setup in intensity modulated proton therapy (IMPT) treatment for localized prostate cancer patients based on a proof of principle study. MATERIALS AND METHODS Three patients with localized prostate cancer retrospectively selected from our institution were studied. For ...
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ژورنال
عنوان ژورنال: Medical Physics
سال: 2017
ISSN: 0094-2405
DOI: 10.1002/mp.12001